49ers head to new home in Arizona to host Bills

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The San Francisco 49ers will need to get used to their temporary new home, while the Buffalo Bills will try to put aside the bad memories from their most recent trip to Arizona. The Niners have relocated to Arizona for three weeks after strict new COVID-19 protocols in their home county prohibited contact sports and practices. ''This entire year has been kind of odd, kind of strange,'' 49ers linebacker Fred Warner said.

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