Yes. I try to backpack when I can, but I find that the lack of water sources in Southern Nevada mean that I'm carrying a lot of weight on my back. And I just don't currently have the time to do a 6 hour drive someplace and then take 3-5 days backpacking (although, West Clear Creek is kinda close).
We can discuss gear all day long, but the bottom line is that you require far less than you think you need, and I recommend that you check out ultralight backpacking tips.
The gear can get expensive, but saving as much weight on your back as possible is worth it.
FWIW, here's my general gear list: Gregory Baltoro 65L; Half Dome 2 Plus (b/c I'm long - and it's heavy - and I've been seriously considering either changing to a tarp or a hammock), mummy bag, Air Rail pad (side sleeper, and I'd like to eventually just go to a quilt), JetBoil Flash (although I've been thinking about changing); water filter, water bottle (and a roll-up Platty bottle); FAK; hat; clothes (just don't change, other than maybe have a set of socks and a bag baselayer); headlamp; external battery; groom kit; rain shell (usually just a jacket - if I need pants, I seriously consider going out at all); trekking poles.
Best endurance builder - small day pack, load it 10-15 lbs, go dayhike.
My 2 cents. YMMV.