IMQ #28 - People in Film - Best Female Comic Performance

[Chaplin]

Claudette Colbert - It Happened One Night

Honorable Mentions:
Melissa McCarthy - Spy
Rosalind Russell - His Girl Friday
Katherine Hepburn - Philadelphia Story/Bringing Up Baby
Holly Hunter - Raising Arizona
Marilyn Monroe - Some Like It Hot
Diane Keaton - Annie Hall/Manhattan Murder Mystery

 

[AzStevenCal]

Irene Dunne - The Awful Truth
Doris Day - Glass Bottom Boat
Barbra Streisand - Mirror Has Two Faces
Anna Kendrick - Pitch Perfect
Barbra Streisand - What's Up Doc
Emma Stone - Easy A
Diane Keaton - Something's Gotta Give
Debbie Reynolds - Tammy and the Bachelor
Sally Field - Smokey and the Bandit
Goldie Hawn - Overboard
June Allyson/Carole Lombard - My Man Godfrey

 

[Cheesewater]

Lili Tayor - The Impostors
Marilyn Monroe - How to Marry a Millionaire
Marisa Tomei - My Cousin Vinny
Shirley MacLaine - The Apartment
Meg Ryan - Joe Versus the Volcano

 

[AzStevenCal]

Lili Tayor - The Impostors
Marilyn Monroe - How to Marry a Millionaire
Marisa Tomei - My Cousin Vinny
Shirley MacLaine - The Apartment
Meg Ryan - Joe Versus the Volcano

From your other posts (and my other posts), it's clear that our movie tastes couldn't be much further apart. But I have to second your mention of Marisa Tomei. She was perfect in MCV.

 

[MadCardDisease]

Rebel Wilson - Pitch Perfect