Great, great movie! In short, how a superhero movie (or any summer blockbuster) should be done.
This is what happens when you have a great director doing a superhero movie that he also happens to be a big fan of (He has admitted to being a Spiderman geek and as you will find out shortly so am I). He remains pretty faithful to the comic book, which can be a pretty tough thing to do.
I was originally a bit frightened by the choice of Molina to play Doc Ock, not because of his acting skills (I actually think he is a highly under-rated actor), but because of him getting the look and not being able to be the character fully (Otto Octavius is Russian and I didn't see Molina talking with a Russian accent. Thankfully they went away from that). However, I'm glad to say that my fears were eased and Molina did a fantastic job.
Okay now for my like scenarios as it comes to the sequels (if you haven't read the comic book and/or don't want things possibly spoiled don't highlight)...
**** Comic Book Spoilers ****
As it comes to the 3rd movie its all but a given that Harry Osborne will turn into the Hobgoblin and be the main villain in the movie. What the also could do as Djaughe eludes to is have Spidey after fighting the Hobgobin save JJJ's son from a shuttle crash and discover the alien costume.
Then during part 4 have Spidey one of the supervillains left such as Mysterio (I think a good choice for a viilain in one of the movies), Scorpion, Vulture, The Lizard, etc. in the alien costume and introduce Eddie Brock and why he is so hell bent against Peter Parker. There is also the possibility of introducing the Black Cat into this (in the credits they have Felicia Hardy mentioned in part 2 although I don't remember her being introduced) to make life more interesting for Peter Parker in his personal life as well as his superhero life. As the movie ends have Spidey go against the alien costume and have it attach to Eddie Brock.
Then for part 5 have Spiderman versus Venom.
The reason you don't want to rush into having Venom as a villain is due to the reason that the reason that Venom was such a thorn in Peter's side was because as he wore the Symbiate, the costume learned all about Spiderman/Peter Parker (his strengths, weaknesses, memories, etc). If you rush the character in, you lose that aspect.
Then for the sequels thereafter, they could have a wide variety of villains left and eventually introduce Carnage.
Okay now back to part 2 ...
I'm disappointed that they killed Doc Ock since I wanted one of the sequels to have the Sinister 6 and that wouldn't be the same without Doc Ock (although I'm not completely sure he's dead).
I was also hopeful that the reason that Spidey was having troubles wasn't psychosematic but a future introduction to when Peter Parker becomes Man -Spider.
Other than that I absolutely loved it