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Who knows. Can he get in better shape so that you don't have to pull him off the field so often? Will he stay in shape once he has some success? Those are questions you have to ask for any 1st round DT, let alone a potential 1st overall DT. Can he destroy an offensive gameplan? Because that's what you need from any 1st overall pick on defense.
Bosa has other question marks. His ceiling seems capped, but looks like he will still be a good pro. Imo a safer bet than Quinnen. If we go defense with the 1st overall pick, I tend towards Bosa. Outstanding technician who will earn his sacks, especially if he starts his career across from an All-Pro like Chandler Jones and learning from a future HoFer in Suggs. Being close to his brother who knows a thing or two about pass rushing won't hurt either. Will Nick Bosa be an All-Pro though? Will he affect the offensive gameplan? That's what you shoot for with the 1st overall pick.
Being safe with your 1st overall pick is one thing, but the capped upside should make us explore other options closely. Remember how many "safe" 1st round picks in recent years have underachieved or busted. In this case, you not just missed on a high ceiling player, but also on the expected "safe floor". It's really tough to find the right balance. If we are 100% sure about Bosa or Quinnen, we should go ahead and select one of them. However, will they ever be game changers? Kyler Murray is without a doubt a riskier prospect than Bosa, although the risk gets way overblown imo because of one or two inches. You can't teach accuracy Keim says. Athleticism obviously as well. We don't need to discuss who of all these top prospects has the highest ceiling and which position is the most important on the field. That's my point. If we evaluate that Bosa (or Quinnen) is a slam dunk with a high floor and great upside that can be achieved realistically, just go for it. However, if there are questions about them fulfilling their potential, you know who the pick should be...
I think every pick has question marks. The idea of drafting Bosa because of his pass rush abilities excite me along with Chandler Jones. However, I think Williams can anchor the Cardinals defensive line which is why I consider him a safe pick.
If I were going to go for pure upside I like Murray but I don't think it is a smart idea to give up on Rosen. The Cardinals would likely regret it especially if Murray doesn't live up to expectations. This is why I have always been a proponent of the Cardinals keeping Rosen until they know for sure who is their QBOTF.
If the Cardinals have question marks who they should draft at #1... trade down.