I think it is beyond foolish to make any prediction on number of wins and losses at this point. I will, however, make a few predictions:
A new offensive system will take time to digest and the early going will be rough.
Wiz will make a couple horrible mistakes in his first shot at running a pro game and will cost the team a win or two early on. Hopefully he will learn from those mistakes.
The OL will be no better than last year, and maybe worse even with Grimm on board...especially if Davis goes and without further upgrades.
Edge and Wiz will clash over the whole "I train preseason in Miami and don't play preseason games" stance.
There will be alot of bitching about Rod's first draft A.D. (After Denny).
Everyone will see that the Db's will still be 10 yards off WRs since they simply cannot cover people right and the door to move Antrel to S has closed with the Francisco extension.