Meh. Too many factors to really take a stance either way.
1-How many top end players are there in the draft?
2-How far do you have to go back?
3-What are you getting for it?
In this draft, I see three top, non-QB prospects. Quinnen Williams, Nick Bosa, and Ed Oliver. Oliver is more of a scheme dependent play IMO, but I could be wrong. All of these should be plug and play starters. The biggest argument for trading down that I see is that this draft is really strong with DL. There are probably 10 other defensive line prospects with first round grades on them, and i feel like I am conservative with that statement. Personally, I feel that the DL position is so valuable that you have to come away with one in your first two picks regardless of what you do early.
There are also a couple other players who I feel are legitimate players and fill HUGE needs.
TE-There are four worth top 60 consideration. Noah Fant, Irv Smith, TJ Hockenson, and Albert Okweugbunem. Rosen would benefit from a young TE who can catch. I hoped that RSJ could be this player, but his struggle catching the ball is tough to swallow. Each of these guys are legitimate prospects who are also at a position of need.
OL-Is the biggest need, but also probably the biggest reach as no player really grades out as a top 10 player. Jonah Williams is a nice player and would be good for our line, but he seems to have more of a RT or OG frame. Both of those spots are needs, but I'm not how comfortable I am just taking Jonah even if we can trade back a few picks. Ideally you would trade back to 15 and take him, but there is no guarantee that he is there at 15. I would be more interested in trading up from 33 for a guy I liked. I believe Jonah Williams, David Edwards, Yodney Cajuste, Dalton Risner, Chris Lindstrom, and Isaiah Prince are all top 60 type OL guys who can come in a fill a role on a good line.
There are also a couple areas where needs are high, but I don't see them matching up with a high draft pick.
WR-I get it, we need WRs. But, I don't see a situation where the top guys available are going to line up with where we are picking. I would target WRs in the 3rd round as I think you will see some drop, and there are guys who can fill roles in our offense right away. A bunch can change, but right now, there isn't a WR I am taking in the top 10, and the drop in talent from rounds 2 to 3 in OL and TE is greater than WR.
DB-Yes, we need a #2 CB opposite of Peterson. No, it is not going to be a top 45 drafted rookie. No, we aren't going to take a S. FA could change this, but I believe our defense is going to get bolstered in FA and the middle rounds of the draft are going to be offensive additions. We aren't taking a CB or S in round 1.