Our RB's can't stay healthy enough to run the single t. I wouldn't be oppose to it if our QB situation doesn't get better. Nothing like getting back to the basics.
Rather than refer to the single wing in a narrow sense, we really should define a broader category of direct-snap formations that feature running plays (off zone-reads, jet-sweeps or just plain straight runs by a deep back).
For example, the Pistol is similar to the old Steve Owens "A" formation spinner series and the Wildcat looks a lot like the old Double Wing or like the old Short Punt formation - only with the blocking backs split wide.
Actually, key features of the traditional Single Wing were an unbalanced line (with a weakside guard or tackle moving to the strong side of the center) and a "lopsided backfield (with more backs lined up on the strong side of the deep back). The resulting overload set up all kinds of double-team blocking opportunities. Weaknesses were that blockers had to sustain their blocks longer and plays were often vulnerable to LB's shooting the gaps.
In any case, I do think we'll continue to see a resurgence of deep-snap activity on offense. (But I do agree that teams moving in that direction better line up 4-deep in passing tailbacks (or running QB's) because of the pounding they'd have to absorb).