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Cardinals (6-6) at Giants (5-7)
1 p.m. ET | Fox
Matchup rating: 38.4 | Spread: ARI -1.5 (45)
What to watch for: The Giants have rushed for at least 132 yards in six of their past seven games. This week, they get to face the league's 22nd-ranked rushing attack. How running back Wayne Gallman & Co. do against Arizona's defense will go a long way in determining the final outcome of this contest. -- Jordan Raanan
Bold prediction: Cardinals wide receiver DeAndre Hopkins will have 125 yards and a touchdown, but it won't be enough because the Cardinals will be playing from behind for most of the game. Hopkins hasn't had 100 yards receiving since Week 10, so he's due for a big game. -- Josh Weinfuss
Stat to know: The Giants had 15 turnovers and 10 takeaways in their first eight games. Over their past four, they have committed only two turnovers and secured 10 takeaways.
Playoff/draft picture: Arizona has a 40% chance of making the playoffs, per FPI. Win, and it becomes 51%. Lose, and the Cards are left at 21% to make the postseason. The Giants, meanwhile, enter the week at 57% likely to win the NFC East, and it would rise to 77% with a win.
Injuries: Cardinals | Giants
What to know for fantasy: Cardinals quarterback Kyler Murray's worst three games this season have come in succession, and yet his 308 fantasy points still rank second across all positions. See Week 14 rankings.
Betting nugget: The Giants are 8-2 ATS as an underdog this season with seven straight covers. Read more.
Weinfuss' pick: Giants 24, Cardinals 17
Raanan's pick: Giants 26, Cardinals 23
FPI prediction: ARI, 63.9% (by an average of 4.8 points)