If there are no long-term injuries to key players (Nash, Marion, KT, and I'd hope Banks), then I think we are a good bet, maybe odds-on, to do it. Leaving out Amare eats up some bad karma, in my book, so this is not too unrealistic. And after the first 15 games and KT got acclimated, we were best in the NBA--pretty good defense to go along with usual offense. Compared to then, we have more depth, explosiveness, defense.
For me, the key issue is whether Antoni can wean himself from overplaying players. Even accepting his claim that players must play 25 minutes a night to be effective, we could go 10 deep with each playing 24 minutes. That would be dumb, but we could pretty practically go 9 deep, and easily 8 if we allowed for some 10-minute subs. That allows for 30 for Nash, 35 for Marion.