If he was there at #27 I would take a chance
If we got a high lottery pick only Aldridge should be an option for us really although Marcus Williams, Brandon Roy, Tyrus Thomas might make sense as well.
If we got a pick in the 10-16 range I would not take Sene. Carney, Rondo, Farmar, Rodriguez, Brewer, Armstrong, O'Bryant, Simmons, Sefolosha would be options.
At #21 I think there will be Farmar, Rodriguez or Rondo on the board and maybe Armstrong. I wouldn't pick Sene over them.
At #27 I would take the risk but I have logged in James White as my pick at #27. Maybe even at #21.